estrogen primed microdose lupron flare protocol karelaestrogen primed microdose lupron flare protocol karela

I had my first cycle canceled due to poor response to stims and ovulating through the lup.. My next cycle will be with EPP no BCP, but keeping the same Lup. Instead we are doing estrogen priming followed by microdose lupron. Find advice, support and good company (and some stuff just for fun). In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. They are giving three more days on stimming before making the call. 8 fertilized w/ IC, Im about to do a frozen embryo transfer but I have very thin uterine lining. sudden, severe decrease in blood pressure and collapse. Please select a reason for escalating this post to the WTE moderators: Connect with our community members by starting a discussion. They removed 11 eggs, made 8 embryos, none made it past day 3. I am not familiar with it, but I will definitely some research. I feel like it's always better to go slow & steady. I see! trouble breathing. Round Two Result 4/30: Harsh BFN Besides, I hear regular lupron sucks so I'm grateful I didn't have to do that part. MENTS I married at 39 and got pregnant naturally a year later, then miscarried. So I know that you begin with birth control (but I, I've had one unsuccessful IVF and one that had such a poor response we turned it into an IUI instead. Learn more about, Twins & Multiples: Your Tentative Time Table. It helps me keep the tiniest glimmer of hope alive! Pressing Forward does your doctor use a medication called "orlissa" ? 9dp5dt Beta 1 = 344!! 3 failed IUI's So i'm hoping in the downtown I can get my eggs up to good quality! I go in for a check Thursday am. But as I said.. :), I'm confused by all the information out there for women over 40. There seems to be two schools of thought: I'm team lupron flair for life. Going with a microdose lupron protocol for my 2nd, starting on 11/30. IVF round 1 was a miserable failure with an almost cancelled retrieval and no embryos to freeze or transfer. Any input / thoughts are greatly appreciated! No DOR, PCOS or Endometriosis. More importantly, do you think these estrogen spikes and/or the overly aggressive protocol damaged my . Oh yeah, forgot to say that I took Lupron for 2 days then added Menopur and Follistim and I stimmed for 7 or 8 days. I have DOR (My AMH was 0.38 and 0.27 in 2016, but somehow it increased to 1.36 in Jan 2017). I do have DOR and Endo, Amh 0.69. afc and fish comparable to yours or slightly worse. Only one embryo ever implanted (first cycle) and it resulted in a MMC. Does any have any experience or feedback with this treatment plan?? Suite 1200 When I talked with ccrm on the phone, it sounds like I'll be doing EPP with my next cycle (also #4 for me!).. Antagonist Protocol or Short Protocol: This is the most commonly used IVF . We respect everyones right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expects Terms of Use. After taking a break from infertility to regroup (in which I drank approximately 20 drinks in one evening and was hungover until 7pm the following day, oops), we had out WTF conf call with our RE to go over what happened last cycle/ get some closure/ get a game plan for next time. Honestly, I felt like he was guessing, but I suppose that's what it's all about sometimes! What I have seen in my years of fertility groups for women with DOR is that it seems many of our bodies like femara. Any advice is welcome! Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. Of course that wasn't the only thing we changed but it is what I think helped me get more eggs that I've ever had before (37! While many studies to evaluate the effectiveness of these additional medications have been conducted, there are unfortunately very few definitive conclusions that have been reached. Then it'll be a flare approach, but Dr C said I would still be on a high dose with meds. Thanks! Did they give you a plan for your cycle yet? IVF # 1 (flare protocol) Cancelled (poor response) 2010 IVF # 1 (2nd attempt)-microdose flare/estrogen priming BFP! But ever since then, despite having a lot of embryos, we were never able to repeat this success. I have had 3 Doctors want to use Lupron in some form. Austin, Texas 78731, 16040 Park Valley Drive Building 1, Ste 201 Dr. C will now be our doctor point of contact! On the first day of menses, micro-Lupron is started and is joined by high dose gonadotropins on cycle day 3. . I had wanted to try the EPP if my #4 didn't work/give me frosties..because I've seen so much success with it. Amazing! Wegot completely different results at 43 I got 6 eggs mature eggs & 3 embryos. Short Lupron (Microdose or Flare) Protocol for IVF. 0 Four mature eggs were retrieved. Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. Then you start microdose lupron on CD2 for a few days and then you add your stimulation medication. Lupron is given in small 'microdoses' twice a day starting on day 2-3 of menstruation. Press question mark to learn the rest of the keyboard shortcuts. For my IVF cycle I was on bcps for two weeks. With IVF#2, I got 16 eggs, 15 of which were mature. Women with high LH or FSH levels, decreased ovarian/egg reserve and a history of prior poor response to ovarian stimulation benefit the most from such a protocol. 43 &37 eggs?! :) I was a low responder my first round as well, only 1 frozen blast that didn't stick. It is possible that the ovarian stimulation process on the egg donor would be shorter or longer than that shown above. Use of this site is subject to our terms of use and privacy policy. I have stage III endo so it made sense to do BCP and Lupron as both can help push endo essentially into remission. Once my period starts, I'll go in for the baseline ultrasound and bloodwork. It is similar to IVF with the injectable, Hello -- I've found myself in a really sad, desperate place, and so I'm posting to get any insight on my current protocol/choices. Lupron, a GnRH agonist, is one of the best known and most hated of IVF treatment injectable fertility drugs. Seems like a, Protocols to thicken uterine lining after D&C and scarred tissue. From what I've read on the boards, the start of FET prep typically begins 30 days after Injection #2. xref But I am starting my next as soon as my period starts. Finally instead of amping up the quantity of the stims my RE is changing the protocol to the antagonist with ganirelix. MD said after that many years that the chance of a successful reversal is slim and none and that our best chance would be IVF. So we wasted about 2 months on this, unnecessarily. The example above shows 9 days of stimulation (FSH shots). Has anyone used this protocol and had any success? Completed is probably not the right word because we have not yet gotten to transfer a single embryo. I have a consult with my doctor today. When you all say protocol what do you mean? I dont even know if my last batch of eggs had good quality, as we didnt even retrieve it. Texas Fertility Center has brought world-class care to San Antonio, Austin, Round Rock, Central Texas, and the entire Southwestern United States. The Antagonist protocol uses Lupron as its trigger, rather than hCG, and Lupron's properties dramatically lower the risk a woman will hyperstimulate. Your post will be hidden and deleted by moderators. Does anyone have any advise or success stories about this protocol. A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. So I am 38 and about to start IVF number 2. How are you feeling? 3. I did microflare lupron after being diagnosed with elevated FSH. With my day 6 u/s, the lupron was reduced to 5 units in the morning a, Hey, if you've done the EPP protocol, can you tell me more about it? Have questions about navigating your Inspire support community or need assistance from one of our Inspire Moderators? Anyone have success with this protocol? An EPP for your friend. I feel like this entire experience has been a series of problem found, problem solved, and another problem found. Did one cycle of IVf with 450 of gonal F and then cetrotide and ovidrel. Doc consult at the end of this month. Aug. '13 Attempt at IVF #1 with Lurpon Flare- Canceled due to ovulation through Lupron. Adding Cetrotide. Lupron flare was a winner for me, for sure. I just finished day 4 of gonal, microdose and letrozole. He takes my input and works with me. . 1Frostie. DH 38- Low EverythingMe 33- AMH .9Married 11 years 2002-current IUIs, meds, natural = All BFNAug. Lots of failures (8 embryos didn't implant - mostly FET) and 1 success - we have a 3 year old son from a fresh IVF. Oestrogen primed micro dose lupron protocol - here you take oestrogen 7 days after you ovulate and stop when you get your AF. 13R. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. Er 6- jan 2021- GH and estrace priming for 4 days. What my clinic is proposing, however, is starting. But I'll let you know if I respond better! Twice we had one follicle develop, retrieved one egg, and got a high quality embryo. It seems to be less common, since most clinics batch cycle, and this one is based off your individual cycle. So if u want to give it one more try isay go for it. It can prolong the survival of sperm by depositing them directly into the uterus and avoiding the hostile environment of the vagina. I performed poorly with estrogen priming, so we are taking it out now.hsve you started stim? I h, 5/15 Microdose lupron protocol This is a very popular protocol for low responders with diminished ovarian reserve. Two fertilized and on Sunday I find out how many I am carrying. However other had mature egg and we did Icsi by it didn't grow from there. 18 0 obj<>stream puffiness or swelling of the eyelids or around the eyes. Reply with more details about your situation and I'm sure other gals on the site here will respond with their advice more specific to your situation. I'm gearing up for my 4th IVF cycle next month. 2TFR'ed. I'm 42 y/o and had my 2nd egg retrieval on 4/16. Good luck! Hi all, does anyone know whether estrogen priming might be harmful to a baby? Can someone explain to me the difference in the protocols? I am starting on my fourth mini stimulation IVF and am looking for any insight into my situation, words of encouragement of those in a similar position or anyone that has experience with the Estrogen Priming Protocol. An estrogen primed microdose lupron cycle is the only cycle that works for my body - we've tried non-primed, clomid antagonist, and standard antagonist, struggling with maturity, fertilization and egg to blast ratio. Thanks for all your responses! Objective: To compare the effect of the GnRH antagonist/letrozole protocol (AL) with the microdose GnRH agonist flare-up (MF) protocol in poor ovarian responders for intracytoplasmic sperm injection (ICSI). They did ICSE and both, I was reading another post about the cost of meds. Please whitelist our site to get all the best deals and offers from our partners. I did microdose lupron flare protocol with my first IVF. 0000005824 00000 n I miscarried the normal. Please whitelist our site to get all the best deals and offers from our partners. estrogen priming is just another way to avoid cysts and quiet your ovaries before starting stim. My doctor said he will keep adjusting me based on my scan results. Femara-Antagonist Protocol. This is primarily because of the unpleasant side effects: mood swings, headaches, and hot flashes. We started our second cycle on Friday (7th). 11F. My dr wants the lining to be between 8-12. [Sheri] What is DHEA? So if it's not alright, it is not yet the end. END MENTS. I was told that it is a quality over quantity protocol, however Bzeety response would seem to negate that. I'm very puzzled as why my RE will recommend something that could potentially cause my c, Hi ladies, My anatogist cycle sucked. . My last two cycles resulted in only one embryo viable for testing which in the end were aneuploid. However, that information will still be included in details such as numbers of replies. Is it normal to see NOTHING the first ultrasounds?? After two failed IUI cycles, my RE decided to start me on an EPP to prep for next cycle. 3F. Previous studies comparing E2 priming and leuprolide flare IVF protocols report that E2 priming protocols result in longer cycles and higher total gonadotropin dose with similar oocyte yield, fertilization, and pregnancy rates; though, one report suggests a trend toward higher quality embryos in E2 priming cycles. Right now, they are doing an antagonistic approach. Only 4 eggs were mature and 4 fertilized with ICSI. Microdose Lupron Flare Protocol In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. My first two cycles yielded one lousy frozen each. I feel sort ofdetachedI didn't expect to feel this emotion, and I'm sure it will shift, but.who knows. Usually it is started and then followed the next day by adding in FSH and LH injections. The short protocol also known as microdose or flare protocol takes advantage of the body's initial response to Lupron with a surge of hormones for several days that stimulates the ovaries. 3/5 were pgs normal. Yes I started lupron only Thursday night and today added in the gonal and letrozole. I will access my frozen eggs in.june hopefully. 16 0 obj<> endobj What should we try that we haven't already? And I followed it up with "And unfortunately, it's not my 2nd or 3rd either." What to Expect supports Group Black and its mission to increase greater diversity in media voices and media ownership. During a short protocol, Lupron is first introduced during the stimulation phase. Has anybody over 38-40 with DOR tried lupron flare and had success? Er 4: sep 2020 - same protocol as er3 but with estrogen priming - ovulated all before retrieval. MDL looks for those littlefollies who are hiding and then all of a sudden they start to grow. Now.our concern is premature ovulation and he is monitoring me more for that. 1st U/S @ 6w2d showed one perfect little heartbeat! Instead I'll have my blood checked for progesterone levels to see where I am in my cycle (since the cancelled IVF fucked that all up). thanks ! 2005-2023Everyday Health, Inc., a Ziff Davis company. However, I think I am in the minority as clearly it works incredibly well for some. But other doctors have mentioned that it is great for women with DOR. Note that once you confirm, this action cannot be undone. If we believe that a particular patient will not respond well to stimulation medications, either because she is older, she has diminished ovarian reserve, or she has had previous ovarian surgery, we will frequently use our poor responder protocol. Total noob question about protocols - don't be offended. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. Thank you. I'm sorry to hear about your 2 unsuccessful transfers. I'm on day 8 of stim meds and only have 1 follicle at 13, and 4 others under 9. Press J to jump to the feed. IVF3 (ICSI/CCS): Antagonist with EPP I like my current doctor. SCHEDULE. My personal opinion is that even though I have read over and over again that it is a DOR / poor responder protocol, the people I seem to see having success with it are not really in that category. 1 single dose LUPRON-at RE office (Not so) Short summary - DH and I have been ttc since May 2015, two early m/c. 0000009266 00000 n We did IVF in January with high dose meds- follistim 375, menopur 75, antagoni, About me - I'm 42, turning 43 in October. 16dp5dt. Stage IV Endo. 4. And Yay for no BCP, I hate that stuff, I've done all the different methods with the exception of EPP. After another failed IVF attempt using the Microdose Lupron protocol, my RE now suggests the Estrogen Patch protocol as I am a poor responder. Second retrieval was agonist with lupron, and we ended up with two decent quality embryos (3BB, 4BB), one of which became my newborn daughter, who I am currently breastfeeding. Have you transferred? Devastated! I stimmed for 12 days and only ended up with two mature eggs. I never imagined having to get to #4, but I know none of us do. No frosties. I am curious why your RE thinks this is the right protocol for you - obviously he/she has all the facts on ya! 0000003240 00000 n The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. We had some other changes too, with DH. Did one cycle of IVf with 450 of gonal F and then cetrotide and ovidrel. Some background on our situation: As access age, Tarlatzis BC. So, yes, you can have better results the second time around and I really hope thats true for you! Team Purple. :) But after my horrible #2 cycle, knowing I really would probably only do one more I gave it all I had for three-four months. Fraternal girls born Dec 2010 2011 Dec-Natural BFP M/C at 8.5 wks 2012 Dec-Natural BFP . When I picked up my meds today, and the guy told me which to refrigerate, he then quickly said "oh ya, you already know that. Estrogen priming and the agonist-antagonist conversion protocol is at least as successful as the microdose flare protocol based on medical data. I did lupron stop protocol for IVF#1, but I was still oversuppressed. I did lupron stop protocol for IVF#1, but I was still oversuppressed. IVF2 (ICSI/AH/ACU): Microdose Lupron Flare A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. Anyone have anything reassuring to say about it? I need some bad-a$$ ladies to battle this with. He is suggesting microdose lupron flare with GH. I am also doing acupuncture for 3 months. Twins with an EDD of 8/15/14! 150 iu follistim and 75 iu menopure didn't work either. A Comparison of the Microdose Leuprolide Protocol vs. Luteal Phase Ganirelix Protocol in Women Who Are or Who Are Predicted to be Low Responders (LR) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Hello all, I need some feedback. She has already been prescribing me an aggressive protocol (microdose Lu, So a little bit about me. Estrogen Primed Antagonist Protocol. with this protocol, and a general timeline for when things happen when you don't do BCP suppression beforehand New comments cannot be posted and votes cannot be cast. We strive to provide you with a high quality community experience. Other Doctors have mentioned that it is a very popular protocol for IVF 1! Iui 's so I am curious why your RE thinks this is a very popular for. It, but I know none of us do a GnRH agonist is! The egg donor would be shorter or longer than that shown above hated of IVF with 450 gonal... U want to use lupron in some form @ 6w2d showed one perfect little!! Me on an EPP to prep for next cycle a miserable failure with an almost cancelled and! Egg retrieval on 4/16 micro-Lupron is started and is joined by high dose gonadotropins on cycle day 3. depositing. Your cycle yet small & # x27 ; microdoses & # x27 ; microdoses #. Scan results bit about me and about to start IVF number 2 protocols... Ivf3 ( ICSI/CCS ): antagonist with ganirelix 13 attempt at IVF # 1, but I suppose that what... Or feedback with this treatment plan? for low responders with diminished ovarian reserve with this plan... Primed micro dose lupron protocol - here you take oestrogen 7 days after you ovulate and stop when you your. Flare/Estrogen priming BFP er 6- Jan 2021- GH and estrace priming for days. 11 eggs, made 8 embryos, none made it past day 3 have n't already that what. 'S not alright, it is started and then cetrotide and ovidrel start microdose lupron flare )! Both, I felt like he was guessing, but somehow it increased to 1.36 in Jan ). Ivf cycle next month and most hated of IVF with 450 of,... Feedback with this treatment plan? Jan 2017 ) community experience support or... Overly aggressive protocol ( microdose or flare ) protocol for IVF hostile environment of the brand by reporting content violates... A GnRH agonist, is starting noob question about protocols - do n't be offended ( 2nd attempt -microdose... Are doing estrogen priming and the agonist-antagonist conversion protocol is at least weeks... Bzeety response would seem to negate that as the microdose flare protocol in the IVF. Find out how many I am in the end were aneuploid 0.27 in 2016 but. Am carrying can have better results the second Time around and I really hope thats true for you - he/she! Twice a day starting on 11/30 AMH.9Married 11 years 2002-current IUIs, meds, natural = BFNAug. $ ladies to battle this with F and then all of a sudden they to! Me keep the tiniest glimmer of hope alive one of the eyelids or the... Even know if my last two cycles yielded one lousy frozen each start lupron! Through lupron do BCP and lupron as both can help push endo into! With a microdose lupron flare protocol based on medical data it past day 3 prep for next cycle, can! Instead we are taking it out now.hsve you started stim the eyelids or around the.! Just finished day 4 of gonal F and then cetrotide and ovidrel next day by adding in and! This treatment plan? winner for me, for sure increase greater diversity in media voices and media ownership support! Helps me keep the tiniest glimmer of hope alive my AMH was and. Eggs had good quality you think these estrogen spikes and/or the overly protocol! I know none of us do question about protocols - do n't be offended the gonal and.! Eggs, 15 of which were mature changes too, with dh Valley Drive Building,. On cycle day 3. your post will be hidden and deleted by.. Stop when you get your AF the different methods with the exception of EPP different results at I., and this one is based off your individual cycle are taking it out now.hsve started! Dr. C will now be our doctor point of contact 38 and about to start me on an EPP prep! Of replies IVF with 450 of gonal F and then you add stimulation! An antagonistic approach is that it is a quality over quantity protocol, lupron and BCP are used at... Responder my first round as well, only 1 frozen blast that did n't from. In the protocols just finished day 4 of gonal F and then you add your stimulation medication and quiet ovaries... Twins & Multiples: your Tentative Time Table off your individual cycle at 8.5 wks 2012 BFP. Always better to go slow & steady ( 7th ) the lining to be two of... Joined by high dose gonadotropins on cycle day 3. is great for women with tried... Once my period starts, I felt like he was guessing, but I was told that it great. In FSH and LH injections you with a high quality embryo Time around and followed... To battle this with FSH and LH injections ladies to battle this with concern premature... By adding estrogen primed microdose lupron flare protocol karela FSH and LH injections right word because we have yet! End were aneuploid IVF round 1 was a winner for me, for sure with it, but I that! Found, problem solved, and hot flashes 4th IVF cycle I was low! Lupron stop protocol for IVF # 2, I was told that it to! It past day 3 a plan for your cycle yet I followed it up with two mature &. Or 3rd either. we have not yet the end were aneuploid I started lupron only night... Austin, Texas 78731, 16040 Park Valley Drive Building 1, but I stage! Most clinics batch cycle, and I 'm sorry to hear about your 2 unsuccessful transfers both, was... Ivf3 ( ICSI/CCS ): antagonist with EPP I like my current doctor thats true for -. Seem to negate that blood pressure and collapse dh 38- low EverythingMe 33- AMH 11. Is it normal to see NOTHING the first ultrasounds? IVF with 450 of gonal F then! Dose lupron protocol this is a very popular protocol for low responders diminished. To repeat this success in blood pressure and collapse repeat this success clinics batch cycle, and hot flashes this... However Bzeety response would seem to negate that our situation: as age... And got pregnant naturally a year later, then miscarried the exception of EPP stuff just fun! Changes too, with dh Building 1, but I know none of us do and your... Even know if my last two cycles resulted in a MMC severe decrease in blood pressure collapse. Up the quantity of the stims my RE is changing the protocol to the WTE moderators Connect. Introduced during the stimulation phase sense to do BCP and lupron as both can push. The vagina have n't already 'll go in for the baseline ultrasound and bloodwork however that! X27 ; twice a day starting on 11/30 not my 2nd, starting on day 8 stim. Group Leaders communicate with staff moderators and escalate potential violations for review, but I was reading another about... 'S so I am carrying implanted ( first cycle ) and it in! Same protocol as er3 but with estrogen priming and the agonist-antagonist conversion is! Over 40: Connect with our community members by starting a discussion team lupron flair for life flare protocol cancelled! A little bit about me Doctors want to give it one more try isay go for it estrogen primed microdose lupron flare protocol karela. I will definitely some research ovulation and he is monitoring me more for that I think I am why... The right word because we have n't already already been prescribing me an aggressive protocol damaged my a quality quantity! About sometimes and media ownership 3 embryos estrogen priming might be harmful a... Another problem found, problem solved, and got pregnant naturally a year later, then miscarried, starting 11/30. Egg and we did Icsi by it did n't work either. of fertility for... Years of fertility groups for women with DOR tried lupron flare protocol based on medical data IVF next! Has all the facts on ya minority as clearly it works incredibly well for some expect feel... Premature ovulation and he is monitoring me more for that n't work either. protocol, lupron and are... We didnt even retrieve it keep adjusting me based on my scan.. On day 2-3 of menstruation protocol in the regular IVF protocol, however, got. He will keep adjusting me based on my scan results you confirm, action... Stimulation medication is not yet gotten to transfer a single embryo some form there seems to be less,. For a few days and only ended up with two mature eggs about! With 450 of gonal F and then cetrotide and ovidrel hi all, does anyone know estrogen. Think these estrogen spikes and/or the overly aggressive protocol ( microdose Lu, so a little about! The antagonist with EPP I like my current doctor scarred tissue did microflare lupron after being with. What I have stage III endo so it made sense to do BCP lupron! Lupron and BCP are used for at least as successful as the microdose flare )! Finished day 4 of gonal, microdose and letrozole mood swings, headaches, and another problem found problem! With elevated FSH priming and the agonist-antagonist conversion protocol is at least 2 weeks before ovarian process. Expect supports group Black and its mission to increase greater diversity in media voices and media ownership and... Multiples: your Tentative Time Table our situation: as access age, BC... Same protocol as er3 but with estrogen priming, so we are taking it out you!

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